70,000 MOS / lane4 parallel lanes15 min run · zero downtime< 3% CV diameter~240 µm · 7 nL matrix droplets96 / 384 / 1536 plate-compatible1 – 400 cells per MOSimage-driven PID size control6,000+ hr validated runtimepipettable like a liquid
MOSgenTMPlatform2026 Launch
3D biology with a 2D workflow.
MOSgen is the first benchtop platform built for high-throughput 3D biology. It generates uniform, permeable cell-matrix microdroplets at industrial scale, ready for any standard assay.
≈ 1,750 wells at 40 MOS/well, in 15 minutes. Up to 4 lanes in parallel.
Uniformity
< 3% CV diameter
Image-driven PID size control. Uniform from droplet 1 to 70,000.
MOS size · volume
240µm · 7 nL
ECM-integrated microdroplets. Permeable to stains, antibodies, T-cells.
Drop-in workflow
0new instruments
Flexibility around your existing reagents, labware, and instruments.
What isMOSgen?
3D biology is essential. Scaling it has been impossible — until now.
Drugs fail at a 90% rate because 2D cell and animal models don't translate to human biology. MOSgen produces MOS® — uniform, permeable 3D cell-matrix microdroplets — at industrial scale. Pipettable like a liquid, drop-in compatible with the instruments your team already owns.
Each run: up to 280,000 MOS in 15 minutes, across four parallel lanes, with single-use consumables and zero dead volume. Any cell type. Any standard plate. Any downstream assay.
We're a benchtop instrument company based in Raleigh, NC. Paid evaluation units are placing now with HTS cores, pharma R&D groups, and translational research programs across the US.
MOS produced per lane70,000
Parallel lanes per run4
Run time15 min
MOS starting cell density1 – 400
Diameter uniformity< 3 %
Confirmed matrix compatibilityPEG · Matrigel
Downtime between back-to-back runs0 min
Validated lab runtime6,000+ hr
The environment
Meet MOS®.
Each MOS is a 7 nL, ~240 µm ECM-integrated microdroplet — permeable to stains, antibodies, and T-cells. Pipettable like a liquid, biologically complete inside.
Brightfield · uniform MOS
Fluorescent · live PDO in MOS
Live, inside MOS
See native immune cells find and kill tumor cells. In real time.
Watch a killing event at single-cell resolution, then zoom out to whole-well biology across drug modalities.
— MOS boundary
NSCLC patient-derived MOS
CD45+ immune cells
Epithelial cell death
An endogenous CD45+ immune cell engages an epithelial cell inside the MOS — and the red death signal blooms as it dies.
›NSCLC patient tumor sample encapsulated in MOS, labeled for native CD45+ immune cells and epithelial cell death.
›Epithelial cells stay contained in the MOS. Smaller immune cells move freely — entering and exiting on their own.
›A native immune cell interacts with an epithelial cell — triggering it to die. The red signal blooms in real time, specific to epithelial death.
Now, at well scaleLive killing across two drug modalities.
whole-well
Epithelia
Epithelial death
01 · Immunotherapy
Endogenous T-cells engage and kill in response to a bispecific T-cell engager.
The patient's own immune cells, activated against their own tumor — live at well scale.
whole-well
Epithelia
Epithelial death
02 · Cell therapy
Autologous TILs engage and kill NSCLC tumor cells.
Functional readout for adoptive cell therapy potency — live at well scale.
Inside the platform
What 280,000 MOS in 15 minutes looks like.
Four lanes, one 15-minute runmage-driven PID holds < 3% CV throughout.
Live run · 4 lanes
Ø ~240 µm · CV < 3%
15-minute run
70,000 MOS / lane
WhereMOSgendelivers
Built for the work your team already does — at the scale you've never had.
01 · HTS
High-throughput screening.
Primary and secondary screens. Full multi-compound IC50 curves from a single lane. 96, 384, 1536 plate formats.
02 · Immuno-oncology
BiTEs, ADCs, TCEs, TILs.
Co-cultures with exogenous or endogenous T-cells. Purpose-built for IO programs running primary patient samples.
03 · Functional assays
Single-MOS resolution.
High replicate power per well. Live imaging, flow, viability — no new instrumentation required.
04 · Translational
Patient-derived, in days.
Predict ex vivo responses that map to patient outcomes. Workflows in days, not months.
Get in touch
Tell us what brings you here.
Pick the reason that fits and we'll route your message to the right person.
HQRaleigh, NC · United States
Response timeWithin 24 hours
StatusPlacing Early Access units now
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Thanks — we've got it.
We'll respond within 24 hours to schedule a conversation. In the meantime, feel free to bookmark uniformbio.com — the full site goes live with our product launch.